In vitro activity and killing effect of uperin 3.6 against gram-positive cocci isolated from immunocompromised patients.

نویسندگان

  • Andrea Giacometti
  • Oscar Cirioni
  • Wojciech Kamysz
  • Carmela Silvestri
  • Alberto Licci
  • Giuseppina D'Amato
  • Piotr Nadolski
  • Alessandra Riva
  • Jerzy Lukasiak
  • Giorgio Scalise
چکیده

The in vitro activity of uperin 3.6, alone or combined with six antibiotics, against gram-positive cocci, including Rhodococcus equi, methicillin-resistant staphylococci, and vancomycin-resistant enterococci, was investigated. All isolates were inhibited at concentrations of 1 to 16 mg/liter. Synergy was demonstrated when uperin 3.6 was combined with clarithromycin and doxycycline.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 49 9  شماره 

صفحات  -

تاریخ انتشار 2005